Associate Professor
Senior Scholar, Michael Smith Foundation for Health Research
Director, Division of Mathematical Modeling, British Columbia Centre for Disease Control
Head, Complexity Science for Health Systems Group (CS4HS)
PhD
 
BC Centre for Disease Control
Vancouver, BC
phone: 6047072475
fax: 6046603166

Dr. Babak Pourbohloul received his Ph.D. in theoretical physics from Laval University, Québec, Canada and conducted postdoctoral research at the Institut national de santé publique du Québec.

Dr. Pourbohloul’s research interests center on modeling the transmission dynamics of infectious diseases and the impact of different control strategies on disease dynamics for designing optimal public health policy. He applies mathematics and computer simulation to the study and control of respiratory-borne, blood-borne, sexually-transmitted, vector-borne and water-borne communicable diseases. He has recently co-developed a new mathematical toolkit based on contact network epidemiology. Dr. Pourbohloul is leading three international research projects, funded by the Canadian Institutes of Health Research (CIHR), in the application of network theory to the prediction and control of emerging respiratory-borne infections such as Severe Acute Respiratory Syndrome (SARS) and pandemic influenza. He is also the Principal Investigator of two infectious disease modeling projects funded by the British Columbia Ministry of Health with the objective of providing policy recommendations to government. He is actively involved in modeling the transmission dynamics of sexually-transmitted diseases such as syphilis and chlamydia in sexual networks; modeling the spread of blood-borne pathogens such as hepatitis C among injection drug users; and developing and applying mathematical models to design policy to control the spread of various vaccine-preventable infections such as pertussis and human papilloma virus (HPV) infection.

Selected Recent Publications:

• Davoudi B, Miller JC, Meza R, Ancel Meyers L, Earn DJD, Pourbohloul B. Early real-time estimation of the basic reproduction number of emerging infectious diseases. Phys. Rev. X 2, 031005 (2012).
• Conway JM, Tuite AR, Fisman DN, Hupert N, Meza R, Davoudi B, English K, van den Driessche P, Brauer F, Ma J, Meyers LA, Smieja M, Greer A, Skowronski DM, Buckeridge DL, Kwong JC, Wu J, Moghadas SM, Coombs D, Brunham RC, Pourbohloul B. Vaccination against 2009 pandemic H1N1 in a population dynamical model of Vancouver, Canada: timing is everything. BMC Public Health (2011).
• Pourbohloul B, Kieny MP. Complex systems analysis: towards holistic approaches to health systems planning and policy. Bulletin of the World Health Organization, April 2011.
• Dimitrov NB, Goll S, Hupert N, Pourbohloul B, Meyers LA (2011) Optimizing Tactics for Use of the U.S. Antiviral Strategic National Stockpile for Pandemic Influenza. PLoS ONE 6(1): e16094. doi:10.1371/journal.pone.0016094.
• Bansal S, Read J, Pourbohloul B, Meyers L A. The dynamic nature of contact networks in infectious disease epidemiology. Journal of Biological Dynamics, 2010; 4(5): 478-89.
• Tuite AR, Greer AL, Whelan M, Winter AL, Lee B, Yan P, Wu J, Moghadas S, Buckeridge D, Pourbohloul B, Fisman DN. Estimated epidemiologic parameters and morbidity associated with pandemic H1N1 influenza. Canadian Medical Association Journal. 2010 Feb 9; 182(2): 131-6.
• Meza R, Pourbohloul B and Brunham RC. Birth cohort patterns suggest that infant survival predicts adult mortality rates. Journal of Developmental Origins of Health and Disease. 2010; 1(1): 174-183.
• Miller J, Davoudi B, Meza R, Slim A, Pourbohloul B. Epidemics with general generation interval distributions. Journal of Theoretical Biology. 2010 Jan 7; 262(1): 107-15.
• Bansal S, Pourbohloul B, Hupert N, Grenfell B, Meyers LA. The shifting demographic landscape of pandemic influenza. PLoS ONE. 2010; 5(2): e9360.
• Pourbohloul B, Ahued A, Davoudi B, Meza R, Meyers LA, Skowronski DM, Villaseñor I, Galván F, Cravioto P, Earn DJ, Dushoff J, Fisman D, Edmunds WJ, Hupert N, Scarpino SV, Trujillo J, Lutzow M, Morales J, Contreras A, Chávez C, Patrick DM, Brunham RC. Initial Human Transmission Dynamics of the Pandemic (H1N1) 2009 in North America. Influenza and Other Respiratory Viruses 2009. Vol. 3(5): 215-222.
• Allard A, Noël PA, Dubé LJ, Pourbohloul B. Heterogeneous bond percolation on multi-type networks with an application to epidemic dynamics. Physical Review E. 2009 Mar; 79:036113.
• Noël PA, Davoudi B, Dubé LJ, Brunham RC, Pourbohloul B. Time evolution of epidemic disease on finite and infinite networks. Physical Review E. 2009 Feb; 79:026101.
• Günther O, Ogilvie G, Naus M, Young E, Patrick DM, Dobson S, Duval B, Noël PA, Marra F, Miller D, Brunham RC, Pourbohloul B. Protecting the next generation: What is the role of the duration of HPV vaccine immunity? The Journal of Infectious Diseases. Volume 197, Issue 12, Page 1653–1661, Jun 2008.
• Bansal S, Pourbohloul B, Meyers LA. A comparative analysis of influenza vaccination programs. PLoS Med. 2006 Oct;3(10):e387.
• L. A. Meyers, M. E. J. Newman, B. Pourbohloul, Predicting epidemics on directed contact networks, J Theor Biol. 2005 Nov 18; [Epub ahead of print].
• D. M. Skowronski, M. Petric, P. Daly, R. A. Parker, D. M. Patrick, M. Krajden, E. Bryce, P. Doyle, M. Noble, D. Roscoe, J. Tomblin, TC Yang, B. Pourbohloul, W. Bowie, T. Booth, S. A. Tweed, T. Perry, A. McGeer, R. C. Brunham. Coordinated Response to SARS, Vancouver, Canada; Emerging Infectious Diseases ; www.cdc.gov/eid ; Vol. 12, No. 1, January 2006.
• R. C. Brunham, B. Pourbohloul, S. Mak, R. White, M. L. Rekart. The unexpected impact of a Chlamydia trachomatis control program on susceptibility to re-infection Journal of infectious Diseases, 2005 Nov 15;192(10):1836-44. Epub 2005 Oct 10.
• B. Pourbohloul, L. A. Meyers, D. M. Skowronski, M. Krajden, D. Patrick, R. C. Brunham, Modeling control strategies of respiratory pathogens. Emerging Infectious Diseases, 2005; 11:1249-1256.
• L. A. Meyers, B. Pourbohloul, M. E. J. Newman, D. M. Skowronski, R. C. Brunham, Contact networks and the spread of SARS (Journal of Theoretical Biology 232 (2005) 71–81).
• S. Lena, B. Pourbohloul, R. C. Brunham. Impact of the immune response on transmission dynamics of sexually transmitted infections (The Journal of Infectious Diseases 2005; 191(Suppl 1):S78–84).
• B. Pourbohloul, R. C. Brunham. Network models and transmission of sexually transmitted diseases Sexually Transmitted Diseases (STD), 2004; 31 (6): 388 – 390.

Research Interests: 

  • Application of Complex Network Modeling in Health Systems Research
  • Mathematical Modeling of Infectious Disease Transmission Dynamics
  • Application of Network Theory in the Analysis of the Spread of Disease in Social Settings
  • Nonlinear Time Series Analysis
  • Application of Mathematical Modeling in Public Health Policy Design
  • Dynamical Systems and Chaos Theory
  • Mathematical Epidemiology
  • Spatio-temporal Analysis of Emerging Infectious Diseases

 

Research Grants (Current and Recent): 

Project Title: [Workshop/Meeting Grant] Complex Systems Analysis: Advancing Health System Policy Design and Planning
Funding Agency: Rockefeller Foundation [Bellagio Conference Centre];
Role: Principal Applicant

Project Title: Rapid Pandemic Containment Using Real Time Contact Network Modeling and Wireless Technology
Funding Agency: Canadian Institutes of Health Research (CIHR);
Role: Principal Investigator

Project Title: [Knowledge Translation Grant] Bridging the Gap: A National Modeling Exchange
Funding Agency: Canadian Institutes of Health Research (CIHR);
Role: Principal Investigator

Project Title: Wintertime Seasonality of Influenza and Invasive Bacterial Disease: Influence of Environment, Pathogen Interactions, Time Scales, and Geography
Funding Agency: Canadian Institutes of Health Research (CIHR);
Role: Co-Investigator

Project Title: Integrated assessment of the role of mucus, a non-Newtonian fluid, in management strategies of epidemic-prone, infectious respiratory diseases
Funding Agency: Canadian Institutes of Health Research (CIHR);
Role: Co-Investigator

Project Title: Mathematical and Economic Modeling of HPV Vaccine Strategies Among the MSM Population in British Columbia
Funding Agency: BC Provincial Health Services Authority
Role: Principal Investigator

Project Title: Evaluation of the Impact of Select Community-based Intervention Strategies on the Transmission Dynamics of Influenza
Funding Agency: British Columbia Ministry of Health
Role: Principal Investigator

Project Title: Evaluation of the Impact of Different Infection Prevention Strategies on the Transmission of Influenza in Health Care Facilities
Funding Agency: Public Health Agency of Canada (PHAC);
Role: Principal Investigator

Project Title: CIHR Pandemic Outbreak Team Leader in Mathematical Modeling – Phase 2
Funding Agency: Canadian Institutes of Health Research (CIHR);
Role: Principal Investigator

Project Title: Pan-Canadian Decision-Making Support Network for Pandemic Preparedness
Funding Agency: Canadian Institutes of Health Research (CIHR);
Role: Principal Investigator

Project Title: Improving Effectiveness and Cost-effectiveness of HPV Immunization Strategies in British Columbia and Canada
Funding Agency: Michael Smith Foundation for Health Research (MSFHR)
Role: Principal Investigator

Project Title: An integrated framework of quantitative public health policy design
Funding Agency: Michael Smith Foundation for Health Research (MSFHR)
Role: Principal Investigator

Project Title: Mathematical modeling of pandemic influenza: A bridging science to inform public policy
Funding Agency: Canadian Institutes of Health Research (CIHR);
Role: Principal Investigator

Project Title: Narrowing the Gap Between Men Who Have Sex With Men aware and unaware of their HIV positive status: The need for enhanced prevention for persons with acute HIV infection
Funding Agency: Canadian Institutes of Health Research (CIHR)
Role: co-Principal Investigator

Project Title: Evaluation of Ontario’s Universal Influenza Immunization Program
Funding Agency: Canadian Institutes of Health Research (CIHR)
Role: co-Principal Investigator

Project Title: Public Health Preparedness for the Vancouver 2010 Winter Olympic Games: Developing Network-based Strategies for Major Public Events
Funding Agency: Canadian Institutes of Health Research (CIHR)
Role: Principal Investigator

Project Title: Modeling Pandemic Influenza Preparedness Strategies in British Columbia
Funding Agency: British Columbia Ministry of Health;
Role: Principal Investigator

Project Title: Mathematical Modeling of HPV Transmission Dynamics to Determine Optimal vaccination Strategy for British Columbia
Funding Agency: British Columbia Ministry of Health
Role: Principal Investigator

Project Title: Population-based Estimates of Cost and Quality of Life in Community-dwelling HCV Patients
Funding Agency: Canadian Institutes of Health Research (CIHR)
Role: co-Investigator

Project Title: The Spread and Evolution of SARS Coronaviruses through Contact Networks: Prediction, Recognition and Control
Funding Agency: Canadian Institutes of Health Research (CIHR)
Role: Principal Investigator

Project Title: SARS: A Scientific Collaborative to Support Public Health Response through Vaccination
Funding Agency: Canadian Institutes of Health Research (CIHR)
Role: co-Principal Investigator

Project Title: Mathematical Modeling for Hepatitis C Virus Infection Public Policy Development
Funding Agency: Canadian Institutes of Health Research (CIHR)
Role: co-Principal Investigator