Chris Carlsten, MD MPH is an Associate Professor of Medicine and holds the endowed Chair in Occupational and Environmental Lung Disease at the University of British Columbia. He also holds adjunct positions at the Peter Wall Institute for Advanced Studies, the UBC School of Population and Public Health and the James Hogg Research Centre.
He attended undergraduate and medical school at Stanford University before training in internal, occupational, pulmonary and critical care medicine at the University of Washington. His clinical and research interests center on occupational airways disease, and his efforts have recently resulted in his being granted both the CIHR New Investigator Award and the Career Investigator Award from the Michael Smith Foundation for Health Research.
The Carlsten laboratory focuses on the respiratory and immunological health effects of inhaled environmental and occupational exposures, using diesel exhaust, western red cedar, and phthalates as model inhalants. In particular, the lab uses controlled human exposures to address the synergism due to co-exposure to inhaled particles and allergens in mediating health effects related to asthma induction and exacerbation. An epidemiological complement to the experimental model uses a meta-birth cohort of over 20,000 children to study incident asthma related to air pollution (http://tag.spph.ubc.ca).
As director of the Occupational Lung Disease Clinic at The Lung Centre (Vancouver General Hospital), Dr. Carlsten welcomes patients with concerns regarding occupational or environmental exposures contributing to respiratory disease including asthma, COPD, interstitial lung disease, cancer, and pleural disease.
· (focus: diesel exhaust, respiratory and immunologic effects, oxidative stress)
· (humans; ‘in vivo’)
· (‘synergy’; complementing experimental with epidemiologic models)
· (state-of-the-art lab methods within experiments that concretely address public health concerns)
· (gene-by-environment analysis, recognizing its limitations)