Amee Manges
Academic Rank(s)
Professor, MPH, PhD
Associate Director, Education
Phone
604–822–9203
amee.manges@ubc.ca
Location
2206 East Mall Vancouver, BC V6T 1Z3
Dr. Manges is a Professor in the School and molecular epidemiologist with expertise in metagenomic sequencing and human microbiome research. She supervises a laboratory at the British Columbia Centre for Disease Control (BCCDC) and has conducted clinical investigations of microbiota-related therapies, including fecal microbiota transfer (FMT) to treat diarrhea and sinonasal microbiota transfer (SNMT) to treat chronic sinusitis. She has also investigated the role of estrogen recycling microbial pathways in breast cancer risk, and the role of the maternal and infant gut microbiome in early life child stunting and malnutrition. Her research program examines how the microbiome drives the gastrointestinal, metabolic, neurological and immune systems across the life course.
We ask questions about how communities of microorganisms that normally live within us (the human microbiome) are involved in the development and maintenance of health. We use next generation sequencing (metagenomics) and other technologies to learn about how the microbiome functions.
- Our current projects include:
- (1) investigating how the intestinal microbiome contributes to undernutrition and environmental enteric dysfunction in low resource settings
- (2) testing whether fecal microbiota transplantation (FMT) will decolonize the microbiome of renal transplant patients colonized by highly drug resistant bacteria
- (3) examining resistance gene carriage in response to antibiotic use.
SPPH 503 – Epidemiological Methods 2